If I'm going on the record before the festivities begin:
This weekend is Fabio's to lose. If he can match his settings to the '22 tire, he will win.
Bastianini, Martin and Miller should all be fast. They have riding styles and/or base line settings for the GP22 that work in most conditions. Pecco is still searching, but maybe he finds something this weekend.
We'll find out if Rins has actually matured. I don't think the Suzuki will have race winning pace, based upon their previous statements. If Rins chucks it down the road because he sees the championship lead slipping away, or if he tilts and windmills, trying to win his first race of the season (to legitimize his lead) at home, I guess we'll know he's the same old Alex.
The story of this season seems to be that small changes in settings either make or break tire performance. Suzuki is the lone exception. X-factor could be the cloud cover. Air temp will be 25C on race day. The amount of sun baking the track will alter tire choices and settings for the race, which could make things interesting.