It's been a huge reversal of handling characteristics. Marc is now doing for Honda, what Stoner was doing for Ducati. It is looking increasingly like Marky is at the end of his rope with the ill handling RC213V. Like Stoner after several season on the Duc, he's burning out. It has not happened as quickly as with Stoner, presumably because he is physically and mentally tougher, but the cracks are beginning to show. A rider can only suffer so many high speed crashes before the injuries take their toll. He would do himself a big favor if he left Honda and went with Ducati or Suzuki. He has nothing to prove with Honda.
IMHO - a better choice of tire would at best be a band-aid for HRC. They need to get their heads out of their collective ..... and make some radical changes in the chassis. That's what Ducati finally did, and it paid off.
Michelin tires are a clusterfuck. They have had multiple seasons to get their act together. Bridgestones were so much better across the board, right from the get go. And Bridgestone were at a disadvantage compared to Michelin in that their manufacturing plant is in Japan, far away from any of the European rounds. Essentially, IIRC they designed and built all or most of the tires to be used at all the rounds, something like 6 months before the beginning of the season. Michelin OTH, seems to be making a few virtual SNS (available to all riders) practically on demand, and yet still can't get it right.